Sudhir Sekhri completed his schooling from St Xavier’s High School, Delhi in 1971 and graduated in B.Sc. (Engg/Mechanical) from NIT, Kurukshetra, Haryana in 1976. Since an early age he has been a sports enthusiast. He represented his school cricket team for the last two years in school, represented his college cricket team for all 5 years, captained the college cricket team in the final year of college and represented the Kurukshetra University team as well.

After a 5-year stint in the family manufacturing & export business of electric welding equipment, he diversified to the manufacturing & export business of readymade garments. He has been an Executive Committee member of Apparel Export Promotion Council (AEPC) since 1990, has been Chairman (Export Promotion Committee) of AEPC for several years, Vice Chairman, AEPC for the year 2022 and 2023 and is now the Chairman of AEPC since Jan 2024. He is an Executive Committee member of the Garment Exporters & Manufacturers Association (GEMA) since its inception and is its current Senior Vice President. He has also been an Executive Committee member of Apparel Training and Design Center (ATDC) since 2014 and its current Chairman. He is an Executive Member of Apparel Made-Ups Home Furnishing Sector Skill Council (AMHSSC) since 2023. He is also on the Board of Federation of Indian Export Organizations (FIEO) since Jan 2024.

Sudhir Sekhri is known for his philanthropy, benevolence and humanitarianism. He is one of the early donors to Dharamshila Cancer Foundation and Research Centre, an NGO that started North India's first state-of-the-art comprehensive cancer care and research centre. He is an annual contributor to Vivekanand Kendra Prathisthan to sponsor Child’s Education program. He regularly donates to several Institutions involved in social causes viz Sewa Bharti, Durbal Divyang Kalyan Society, ISCKON etc.